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Alpha-1-Microglobulin

α1-Microglobulin is a low molecular weight glycoprotein and is synthesised by the hepatocytes and lymphocytes. Increased excretion of the α1-Microglobulin is indicative of reduced tubular re-absorption. The conditions associated with the reduced re-absorption are chronic interstitial nephropathy and acute or chronic tubular damage.

Biorex Diagnostics manufactures Alpha-1-Antitrypsin reagents designed for Hitachi 917 systems.

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Description

Product Name CAT.No Size
Alpha-1-Microglobulin Calibrator BXC0887A 1 x 1ml
Alpha-1-Microglobulin Control (Level 1 & Level 2) BXC0889A 2 x 1 x 1ml

 

Product Description

The Biorex Diagnostics A1M Assay is an in vitro diagnostic test designed for the quantitative determination of Alpha-1-Microglobulin (A1M) in human serum, plasma, or urine. A1M is a low molecular weight glycoprotein with important physiological functions, including protection against oxidative stress, binding of free radicals and heme groups, and contribution to the body’s antioxidant defence system. Accurate measurement of A1M levels provides valuable insight into renal tubular function and early kidney damage, making it an important biomarker in clinical diagnostics.

Assessment of A1M is particularly useful for detecting early renal tubular injury, often before changes are observed in traditional kidney function markers. Elevated levels can indicate impaired tubular reabsorption, supporting the diagnosis and monitoring of nephropathy, kidney disease, and other renal disorders. The Biorex A1M Assay delivers precise and reproducible results, enabling clinicians to identify abnormalities early and implement appropriate treatment strategies.

Key Features
• Accurate quantitative measurement of Alpha-1-Microglobulin in serum, plasma, and urine
• Supports early detection of renal tubular damage and nephropathy
• Ready-to-use reagents for streamlined laboratory workflows
• Reliable and reproducible performance across multiple laboratory platforms
• Compatible with automated analysers and manual laboratory protocols

Benefits
The Biorex A1M Assay provides clinically meaningful and consistent data for evaluating kidney function and tubular health. Its high sensitivity allows early detection of renal impairment, supporting improved patient management and disease monitoring. The assay’s reproducibility ensures dependable results across different laboratory environments, while its compatibility with automated systems enhances efficiency and throughput.

Routine use of this assay supports nephrology diagnostics, monitoring of chronic kidney disease, and research into oxidative stress and renal physiology. By providing accurate and timely results, the Biorex A1M Assay enables healthcare professionals to make informed clinical decisions, optimise treatment plans, and improve patient outcomes.

Its precision, reliability, and versatility make it an essential tool for hospital laboratories, diagnostic centres, and research institutions focused on kidney health and disease.

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Additional information

Storage

2-8°C