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Alpha-1-Antitrypsin

α1-Antitrypsin is an acute phase protein. It inhibits proteinase and serine proteases. AAT has a strong binding constant for leukocyte elastase. Increased serum levels are found in acute infection and inflammation, acute malaria, Pregnancy, anabolic steroid therapy and advanced malignant tumours.

Biorex Diagnostics manufactures Alpha-1-Antitrypsin reagents designed for Hitachi 917, CA 180/270/400 Furuno and Daytona systems.

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Description

Product Name Details CAT.No Size
Alpha-1-Antitrypsin Suitable for Hitachi 917 HIT0190A R1: 2 x 20ml R2: 1 x 8ml
Alpha-1-Antitrypsin Suitable for CA 180/270/400 Furuno/ Daytona Series Reagents BXCF190A R1: 3 x 16ml R2: 3 x 5ml

 

Product Description

The Biorex Diagnostics AAT Assay is an in vitro diagnostic test designed for the quantitative determination of Alpha-1-Antitrypsin (AAT) in human serum or plasma. AAT is a major acute-phase glycoprotein that plays a critical role in protecting tissues from proteolytic damage by inhibiting proteases, particularly leukocyte elastase. This protective function is especially important in the lungs, where AAT helps maintain tissue integrity and prevents excessive degradation of connective tissue. Accurate measurement of AAT levels provides valuable clinical insight into inflammatory status, liver function, and pulmonary health.

Assessment of AAT is widely used in the diagnosis and monitoring of AAT deficiency, a genetic condition associated with an increased risk of emphysema, chronic obstructive pulmonary disease (COPD), and liver disease. Reduced levels may indicate inherited deficiency, while elevated concentrations can reflect an acute-phase response to inflammation or infection. By delivering precise and reproducible results, the Biorex AAT Assay supports early detection, disease monitoring, and risk assessment, enabling clinicians to make informed decisions regarding patient care and treatment strategies.

Key Features

  • Accurate quantitative measurement of Alpha-1-Antitrypsin in serum and plasma
  • Supports evaluation of acute phase response, liver function, and pulmonary health
  • Ready-to-use reagents for simplified laboratory workflows
  • Reliable and reproducible performance across multiple laboratory platforms
  • Compatible with automated analysers and manual laboratory protocols

Benefits
The Biorex Assay provides clinically meaningful and consistent data for evaluating inflammatory responses and identifying AAT deficiency. Its high precision ensures dependable results across different laboratory environments, while compatibility with automated systems enhances efficiency and throughput.

Routine use of this assay supports the diagnosis and monitoring of respiratory and liver conditions, including emphysema, COPD, and hepatic dysfunction. It is also valuable in clinical research focused on protease inhibition, inflammation, and genetic disorders. By providing accurate and timely results, the Biorex AAT Assay enables healthcare professionals to optimise patient management, improve diagnostic confidence, and support evidence-based treatment decisions.

Its combination of accuracy, reliability, and versatility makes it an essential tool for hospital laboratories, clinical diagnostics, and research institutions focused on respiratory, hepatic, and inflammatory diseases.

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Additional information

Storage

2-8°C