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VDRL

The Biorex Diagnostics VDRL test is a non-treponemal flocculation test for the detection and titration of reagins.  Reagins are antibodies raised against syphilis induced tissue damage.  VDRL Cardiolipin is an alcohol based solution which comprises of three chemically pure components – cardiolipin, lecithin and cholesterol.  When the antigen is added to the VDRL buffered saline solution, it forms an emulsion of fine particles which flocculate in the presence of reagins.

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Description

Product Name CAT.No Size
VDRL SYVD0005 1x5ml VDRL; 1x60ml Buffer

 

 

Product Description

The Biorex Diagnostics VDRL Test is a rapid non-treponemal flocculation assay designed for the qualitative and semi-quantitative detection of reagins—antibodies produced in response to Treponema pallidum infection. It is a trusted solution for syphilis screening, diagnosis, and monitoring, suitable for clinical laboratories, hospitals, blood banks, and public health surveillance programmes. The assay allows healthcare professionals to identify active infections efficiently, monitor treatment response, and support blood safety initiatives.

This test operates on the principle of flocculation, where positive serum samples react with the cardiolipin–lecithin–cholesterol antigen suspension to form visible clumps. It can be performed as a simple slide test for rapid screening or extended to a semi-quantitative titre determination, enabling precise monitoring of antibody levels over the course of treatment. The VDRL Test is effective in detecting antibodies in both early and late stages of syphilis, making it a versatile tool for routine diagnostic and epidemiological applications.

Key Features

  • High sensitivity and specificity – reliable detection of reagins across early and late syphilis infections
  • Quantitative titration capability – allows clinicians to monitor changes in antibody levels during treatment
  • Rapid visual results – clear flocculation visible within minutes without specialised instrumentation
  • Simple procedure – minimal equipment and training required for routine laboratory use
  • Cost-effective solution – suitable for high-throughput laboratories, blood banks, and large-scale screening programmes

Benefits

Routine application of the Biorex VDRL Test enables accurate detection and monitoring of syphilis antibodies, supporting timely clinical intervention, patient management, and public health initiatives. Its semi-quantitative capability allows healthcare providers to track disease progression and evaluate therapeutic efficacy. The ready-to-use reagents and straightforward procedure reduce handling errors, streamline laboratory workflow, and ensure reproducible, dependable results across multiple samples.

By incorporating the Biorex VDRL Test into standard laboratory protocols, hospitals and diagnostic centres can enhance diagnostic confidence, improve patient care, and maintain efficient workflows. Its combination of reliability, sensitivity, and ease of use makes it an essential tool for syphilis screening, monitoring treatment response, and contributing to blood safety and epidemiological surveillance in both routine and high-volume testing environments.

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2-8°C