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LISS Solution Diluent (For Blood Grouping)

Low-ionic strength solutions (LISS) increase the interaction of antigen and antibody in immuno hematologic reactions.

The solutions reduced of ionic strength are used to accelerate the interaction of antigen and antibody. That solution of saline containing less Na and Cl ions than normal isotonic salt solutions interfere less in the reaction between an antigen and antibody of complementary electrostatic charge. These solutions are known in immunohematology as Low Ionic Strength Saline (LISS). LISS solution is used for preparing 5% red cell suspensions for blood grouping as well as 0.8% red cell suspensions for cross matching, antibody screening, direct anti-human globulin test.

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Description

Product Name CAT.No Size
LISS Solution Diluent (For Blood Brouping) OBGLISS1 500ml

Product Description

The Biorex Diagnostics Low Ionic Strength Solution (LISS) is a ready-to-use reagent designed to enhance antigen–antibody reactions during immunohaematology testing. This LISS solution diluent increases both the rate and sensitivity of serological reactions by reducing the ionic strength of the test environment, allowing laboratories to detect clinically significant antibodies more efficiently. Suitable for blood grouping, crossmatching, and antibody screening, it supports accurate transfusion compatibility testing and improved patient care.

Key Features

  • Enhanced Antigen Antibody Interaction: Improves detection of weak or low-titre antibodies for more sensitive serological testing.
  • Reduced Incubation Time: Accelerates serological reactions, streamlining testing workflow and improving turnaround times.
  • Iso-Osmotic Formulation: Maintains red cell stability and morphology, ensuring reliable performance throughout testing.
  • Ready-to-Use Reagent: Eliminates dilution steps, reduces preparation errors, and minimises variability between operators.
  • Versatile Laboratory Application: Compatible with routine blood grouping, crossmatching, and antibody screening in immunohaematology laboratories.

Benefits

Biorex LISS solution diluent supports fast, accurate immunohaematology testing by improving antibody detection and reducing incubation time. Its ready-to-use formulation enhances laboratory efficiency, reduces manual handling, and provides consistent assay performance essential for transfusion compatibility testing. By improving sensitivity, the reagent helps identify clinically significant antibodies that may impact transfusion decisions, contributing to safe blood component selection and optimal patient outcomes.

Routine use of this LISS solution diluent supports reliable workflow standardisation within hospital blood banks, clinical laboratories, and transfusion services. With its combination of sensitivity, operational efficiency, and performance consistency, the reagent is an essential tool for laboratories aiming to maintain high standards of serological testing and transfusion safety.

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Additional information

Storage

2-8°C