The Biorex Diagnostics Alpha-Fetoprotein (AFP) kit is intended for the quantitative determination of AFP concentration in human serum by a microplate chemiluminescence assay.
Alpha-Fetoprotein (AFP) is a glycoprotein with a molecular weight of 70kDA. AFP is normally produced during foetal development by the hepatocytes, yolk sac and to a lesser extent by the gastrointestinal tract. Serum concentrations reach a peak level of up to 10 mg/ml at twelve weeks of gestation. This peak level gradually decreases to less than 25 ng/ml after one year postpartum.