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Kaolin Clotting Time

The Biorex Diagnostics Kaolin Clotting Time reagent for the detection of Lupus anticoagulants.

Lupus Anticoagulants (LA) are frequently investigated in thrombophilic patients or women with foetal loss. The LA antibodies recognize the Prothrombin-phospholipid complex, thereby inhibiting the phospholipid dependent coagulation reactions. The Kaolin Clotting Time kit is the most sensitive test for the detection of circulating anticoagulants. The kit detects all classes of inhibitors, including those directed against factor VIII and contact activation as well as heparin. To overcome this, more specific tests have been developed such as DRVVT tests, which bypass most of the upper stages of clotting mechanism.

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Description

Product Name CAT.No Size
Kaolin Clotting Time COAG121A R1: 1 x 2ml R2: 1 x 2ml

 

 

Product Description

The Biorex Diagnostics Kaolin Clotting Time (KCT) reagent is a highly sensitive in vitro diagnostic assay designed for the detection of Lupus Anticoagulants (LA) in human plasma. By specifically activating the intrinsic coagulation pathway with kaolin, the KCT reagent provides accurate and reproducible screening for circulating inhibitors, including those associated with thrombotic disorders, autoimmune conditions, and other coagulation abnormalities. Its reliable performance makes it an essential tool for clinical laboratories, haematology departments, and research facilities that require precise identification of LA and related coagulation inhibitors.

Key Features

  • High Sensitivity – Capable of detecting Lupus Anticoagulants at low levels, reducing the risk of false negatives.
  • Effective Thrombosis Screening – Supports identification of patients at increased risk of thrombotic events or clotting complications.
  • Versatile Laboratory Use – Suitable for both manual and automated coagulation systems, enabling integration into a variety of workflow settings.
  • Detection of Factor VIII Inhibitors – Identifies abnormalities in the contact activation pathway for comprehensive coagulation assessment.
  • Consistent Quality – Manufactured to strict quality standards, ensuring reproducibility and reliability for routine clinical use.

Benefits

The KCT reagent facilitates sensitive and dependable detection of Lupus Anticoagulants, helping clinicians assess thrombophilia, autoimmune disorders, and associated complications such as recurrent miscarriage or unexplained clotting events. By providing consistent analytical performance, the assay allows laboratories to deliver accurate results efficiently, supporting confident clinical decision-making and optimal patient management. Its streamlined workflow and reproducible output reduce assay variability, ensuring that testing can be reliably applied across routine screening, confirmatory studies, and specialised research investigations.

With its combination of sensitivity, precision, and ease of integration, the Biorex Diagnostics KCT reagent is an indispensable tool for laboratories focused on haemostasis, thrombotic risk assessment, and autoimmune-related coagulation testing. It contributes to enhanced diagnostic confidence, improved patient care, and consistent laboratory efficiency.

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Storage

2-8°C