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Fibrinogen Degradation

Thrombin converts soluble fibrinogen into insoluble fibrin, which when cross-linked becomes the fibrin clot as the last step in the coagulation cascade. Fibrinogen is an acute-phase reactant protein in that the concentration rises sharply in response to many different physiological stimuli such as tissue inflammation or injury. High fibrinogen levels are associated with atherosclerotic cardiovascular disease and with the occurrence of myocardial infarction and stroke.

Other conditions in which fibrinogen is elevated are cancers of the stomach, breast, or kidney, and inflammatory disorders like rheumatoid arthritis. Reduced fibrinogen levels are prevalent in liver disease, prostate cancer, lung disease, bone marrow lesions, malnourishment, and disseminated intravascular coagulation. Other conditions of deficient fibrinogen are congenital afibrinogenaemia, hypofibrinogenaemia, and dysfibrinogenaemia.

The Biorex Diagnostics Fibrinogen reagent is an in vitro diagnostic assay intended for quantitative determination of fibrinogen in plasma.

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Description

Product Name CAT.No Size
Fibrinogen Degradation Products (FDP) COAG114A 60T

 

 

Product Description

The Biorex Diagnostics Fibrinogen Reagent is a high-performance in vitro diagnostic assay designed for the quantitative determination of this essential coagulation factor in human plasma. As a key contributor to haemostasis and an important acute-phase reactant, it plays a central role in clot formation, cardiovascular health, inflammatory processes, and systemic disease evaluation. Accurate measurement of this parameter is vital for assessing bleeding risk, thrombotic disorders, and abnormal coagulation activity in clinical laboratory settings. The reagent delivers reliable and reproducible results to support confident interpretation for diagnosis, monitoring, and patient management.

Engineered for versatility and ease of use, the assay enables precise quantification using established coagulation methodologies and is compatible with a wide range of automated analysers. Its consistent analytical performance ensures dependable measurement across both elevated and reduced concentrations, helping clinicians detect abnormalities associated with congenital deficiencies, acquired disorders, liver disease, disseminated intravascular coagulation (DIC), inflammatory states, and cardiovascular risk profiles. The reagent is particularly valuable for laboratories requiring high-throughput, cost-effective testing without compromising diagnostic accuracy or turnaround time.

Key Features

  • Quantitative assessment of plasma levels
  • Supports comprehensive evaluation of haemostasis and cardiovascular risk
  • Detects reduced and elevated concentrations with high precision
  • Rapid, reliable performance suitable for automated coagulation systems
  • Consistent, high-quality results for routine diagnostic workflows

Benefits

The Biorex Diagnostics Fibrinogen Reagent enhances laboratory capabilities by enabling precise evaluation of a crucial coagulation factor and inflammatory marker. Its analytical reliability improves diagnostic confidence and provides clinicians with critical data for patient risk assessment, therapeutic decision-making, and monitoring of disease progression. Suitable for routine haemostasis investigations, preoperative screening, and specialised coagulation studies, the reagent supports efficient laboratory workflows and contributes to improved clinical outcomes. Its robust performance and compatibility with modern diagnostic platforms make it an essential tool for hospitals, clinical laboratories, and reference centres engaged in comprehensive coagulation testing.

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Storage

2-8°C