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Weil-Felix

The Weil-Felix test was developed by Weil and Felix in 1916. It is a heterophile agglutination test due to the antigenic sharing between species of proteus and rickettsia. Antibodies produced against rickettsial antigen cross reacts with OX19 and OX2 strains of Proteus vulgaris and OXK strains of Proteus mirabilis. Proteus stained febrile antigen suspensions can be used to identify and quantitate specific antibodies in human sera following infection with certain Rickettsiae pathogens. Proteus OX19 reacts strongly with the sera of patients with typhus group rickettsae and rocky mountain of spotted fever, Proteus OX2 reacts strongly with sera of patients with spotted fever infections, while the Proteus OXK reacts strongly with the sera of patients infected with scrub typhus.

The Biorex Diagnostics Febrile Antigens Weli-Felix test is prepared for the rapid detection and semi-quantitation of serum antibodies developed during the acute stage of disease. The antigens agglutinate in the presence of the homologous antibodies in the sample tested.

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Description

Product Name CAT.No Size
Weil-Felix FEWF0025 5 x 5ml

 

 

Product Description

The Biorex Diagnostics Weil-Felix Test is a rapid slide agglutination assay for the qualitative and semi-quantitative detection of antibodies produced in response to Rickettsial infections. Using Proteus OX19, OX2, and OXK stained febrile antigen suspensions, it provides a reliable method for early identification and monitoring of typhus, spotted fever, and scrub typhus.

Key Features
• High sensitivity and specificity – detects antibodies to multiple Rickettsial pathogens
• Rapid visual results – clear agglutination within minutes
• Semi-quantitative – enables titre estimation to monitor disease progression
• Versatile sample use – suitable for human serum and plasma
• Cost-effective testing – ideal for routine laboratory screening and public health surveillance

Benefits
The Weil-Felix Test enables timely detection of Rickettsial infections, supporting accurate diagnosis and effective patient management. Its simple, fast procedure enhances laboratory workflow, while reliable results assist public health authorities in outbreak monitoring and disease control programmes.

Additional information

Storage

2-8°C