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Proteus

The Weil-Felix test was developed by Weil and Felix in 1916. It is a heterophile agglutination test due to the antigenic sharing between species of proteus and rickettsia. Antibodies produced against rickettsial antigen cross reacts with OX19 and OX2 strains of Proteus vulgaris and OXK strains of Proteus mirabilis.

The Biorex Diagnostics Proteus OX19 stained febrile antigen suspension can be used to identify and quantitate specific antibodies in human sera following infection with certain Rickettsiae pathogens. Proteus OX19 reacts strongly with the sera of patients with typhus group rickettsae and rocky mountain of spotted fever.

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Description

Product Name CAT.No Size
Proteus OX19 (OX19 Antigen) FEPOX905 1 x 5ml
Proteus OX19 (OX2 Antigen) FEPOX205 1 x 5ml
Proteus OX19 (OXK Antigen) FEPOXK05 1 x 5ml

 

 

Product Description

The Biorex Diagnostics Proteus OX19 Febrile Antigen is a heterophile agglutination assay designed for the qualitative and semi-quantitative detection of antibodies in human serum following infection with typhus group Rickettsiae. Based on the classic Weil-Felix reaction, this test exploits the antigenic cross-reactivity between Proteus species and Rickettsia, providing a simple, reliable, and cost-effective method for the serological diagnosis of typhus and related rickettsial infections. Its ease of use, rapid results, and dependable performance make it suitable for clinical laboratories, hospitals, diagnostic centres, and field epidemiology applications.

Key Features

  • High sensitivity and specificity – accurately detects antibodies to typhus group Rickettsiae for reliable diagnosis
  • Rapid visual results – clear agglutination within minutes without the need for specialised equipment
  • Simple procedure – minimal laboratory setup required, making it suitable for both hospital and field use
  • Cost-effective – ideal for large-scale screening, routine diagnostics, and epidemiological surveillance
  • Versatile applications – supports clinical diagnosis, monitoring of therapeutic response, and public health investigations

Benefits
Routine use of the Proteus OX19 Febrile Antigen test enables healthcare professionals to detect typhus infections early, facilitating timely intervention and improved patient outcomes. Its semi-quantitative capability allows clinicians to estimate antibody titres, monitor disease progression, and assess the effectiveness of therapy. The ready-to-use reagent eliminates the need for complex preparation, reduces handling errors, and streamlines laboratory workflow, making it especially suitable for high-throughput or resource-limited settings.

Beyond individual patient care, the test is a valuable tool for public health and epidemiological monitoring. By enabling rapid detection of typhus antibodies in populations, it supports outbreak investigations, disease surveillance programs, and the implementation of preventive measures to control the spread of rickettsial infections.

The Biorex Proteus OX19 Febrile Antigen combines speed, accuracy, and simplicity, making it a trusted solution for clinical, diagnostic, and public health laboratories. Its robust performance ensures reliable results, timely diagnosis, and effective management of typhus and related Rickettsial diseases.

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2-8°C