Lipoprotein

The Biorex Diagnostics Lipoprotein assay is intended for the in vitro quantitative determination of human lipoprotein (a) in human serum and plasma.

Lipoprotein (Lp) (a) is a human serum protein whose structure is close to that of LDL. Its density lies between those of LDL and HDL. The Lp(a) concentration in blood varies from almost undetectable levels to more than 100 mg/dl. The wide differences in Lp(a) levels are largely due to hereditary factors and cannot be controlled by dietary or lifestyle changes. The presence of high Lp(a) levels in serum is a significant marker of increased risk for atherosclerosis and coronary heart disease. Epidemiological studies have shown that people with normal serum cholesterol and a serum Lp(a) level over 30 mg/dl have a double risk of coronary heart disease. The risk is 8 times higher when LDL and Lp(a) levels are simultaneously elevated.