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Lipoprotein

The Biorex Diagnostics Lipoprotein assay is intended for the in vitro quantitative determination of human lipoprotein (a) in human serum and plasma.

Lipoprotein (Lp) (a) is a human serum protein whose structure is close to that of LDL. Its density lies between those of LDL and HDL. The Lp(a) concentration in blood varies from almost undetectable levels to more than 100 mg/dl. The wide differences in Lp(a) levels are largely due to hereditary factors and cannot be controlled by dietary or lifestyle changes. The presence of high Lp(a) levels in serum is a significant marker of increased risk for atherosclerosis and coronary heart disease. Epidemiological studies have shown that people with normal serum cholesterol and a serum Lp(a) level over 30 mg/dl have a double risk of coronary heart disease. The risk is 8 times higher when LDL and Lp(a) levels are simultaneously elevated.

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Description

Product Name Format CAT.No Size
Lipoprotein (a) Immunoturbidimetric without sample pre-dilution LS BXC0130A R1: 2 x 20ml R2: 1 x 8ml

 

Product Description

The Biorex Diagnostics Lipoprotein(a) [Lp(a)] Assay is a ready-to-use immunoturbidimetric test for the quantitative measurement of Lp(a) in human serum and plasma, providing essential information for cardiovascular risk assessment and early detection of atherosclerotic disease. Lipoprotein(a) is a low-density lipoprotein variant with an attached apolipoprotein(a) component, and elevated levels are strongly associated with an increased risk of cardiovascular events, including coronary artery disease, stroke, and peripheral vascular disease. Unlike traditional lipid markers, Lp(a) levels are largely genetically determined and remain relatively unaffected by lifestyle factors, making it a critical biomarker for identifying inherited cardiovascular risk.

Key Features

  • Quantitative determination of Lp(a) in serum and plasma
  • Clinically relevant for cardiovascular risk assessment and early detection of atherosclerosis
  • Reflects genetically determined lipid risk factors independent of lifestyle influences
  • Ready-to-use reagents streamline laboratory workflow and ensure consistent, reproducible results
  • High sensitivity and specificity suitable for clinical diagnostics and research applications

Benefits
The Biorex Lp(a) Assay delivers precise, reliable, and reproducible measurements, supporting cardiovascular risk stratification, screening, and long-term patient monitoring. Its accuracy enables clinicians to identify individuals at increased genetic risk of cardiovascular disease who may not be detected through conventional lipid testing alone. By providing valuable insight into inherited lipid abnormalities, the assay supports more comprehensive risk assessment and personalised patient management strategies.

This assay is particularly valuable in cardiology laboratories, lipid clinics, and research institutions focused on cardiovascular disease and metabolic health. Its ready-to-use formulation simplifies laboratory workflows, reduces preparation errors, and ensures consistent performance across a range of testing environments. Compatibility with automated analysers allows for efficient integration into routine clinical chemistry workflows, supporting high-throughput testing and reliable result generation.

In addition to clinical diagnostics, the assay supports research into lipid metabolism, genetic risk factors, and the pathophysiology of atherosclerosis. Its ability to provide consistent and accurate Lp(a) measurements makes it an essential tool for advancing understanding of cardiovascular disease mechanisms and improving patient outcomes.

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