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Kappa Light Chain Reagents

The Biorex Diagnostics Kappa Light Chains Reagent is intended for the quantitative in vitro determination of bound and free immunoglobulins of the Kappa type in serum or Plasma.

Measurement of light chains immunoglobulin types help in the diagnosis of Multiple myeloma, Waldenstroms macroglobulinemia and lymphocytic neoplasms. Various connective tissue disorders such as rheumatoid arthritis and systemic lupus erythematosus have increased production of light chain types.

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Description

Product Name Format CAT.No Size
Kappa Light Chains Immunoturbidimetric without sample pre-dilution LS BXC0331A R1: 2 x 20ml R2: 1 x 8ml

 

Product Description

The Biorex Diagnostics Kappa Light Chain Assay is a ready-to-use immunoturbidimetric test for the quantitative measurement of kappa light chains in human serum and plasma, supporting the diagnosis and monitoring of haematological and autoimmune disorders. Immunoglobulin light chains are components of antibodies produced by plasma cells, and abnormal levels of kappa light chains, particularly when evaluated alongside lambda light chains and the kappa:lambda ratio, can indicate the presence of monoclonal gammopathies and other plasma cell disorders. Accurate measurement is essential for identifying, diagnosing, and monitoring conditions such as multiple myeloma, Waldenström’s macroglobulinaemia, and lymphoproliferative diseases, as well as certain autoimmune conditions where immune dysregulation may affect light chain production.

Key Features

  • Quantitative measurement of bound and free kappa light chains
  • Clinically relevant for multiple myeloma, Waldenström’s macroglobulinaemia, and lymphoproliferative disorders
  • Detects kappa chain elevations in autoimmune conditions such as rheumatoid arthritis and SLE
  • Reliable turbidimetric methodology ensures accurate and reproducible results
  • Ready-to-use reagents streamline workflow and reduce potential laboratory errors

Benefits
The Biorex Kappa Light Chain Assay delivers precise, reliable, and reproducible measurements, supporting diagnosis, disease monitoring, and research into haematological malignancies and immune-mediated disorders. Its analytical robustness enables clinicians to detect abnormal kappa light chain production and assess clonal plasma cell activity, aiding in the identification of monoclonal gammopathies and related conditions. When used in conjunction with lambda light chain measurements, the assay provides valuable insight into the kappa:lambda ratio, enhancing diagnostic accuracy and clinical interpretation.

This assay is particularly valuable in haematology laboratories, immunology departments, oncology clinics, and research institutions focused on plasma cell disorders and immune system abnormalities. Its ready-to-use format simplifies laboratory workflow, minimises pre-analytical variability, and ensures consistent performance across different testing environments. Compatibility with automated analysers allows seamless integration into routine clinical chemistry platforms, supporting high-throughput testing while maintaining accuracy and reliability.

In addition to clinical diagnostics, the Biorex Kappa Light Chain Assay supports research into immunoglobulin production, monoclonal gammopathies, and immune regulation, making it an essential tool for advancing understanding of haematological and immunological diseases and improving patient outcomes.

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Storage

2-8°C