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D-3 Hydroxybutyrate

The Biorex Diagnostics D3-Hydroxybutyrate test is intended for the quantitative in vitro determination of D-3-Hydroxybutyrate in serum and plasma.

D3-Hydroxybutyrate is mainly produced in the liver from oxidation of fatty acids and is transported to peripheral tissues for the production of energy. D3 Hydroxybutyrate forms about 80% of all ketone bodies that result from the oxidation of fatty acids in the liver. High levels of ketone bodies in blood causes ketosis. Normal ketosis is prevalent in conditions such as fasting, prolonged exercise or a high fat diet. Causes of pathologic ketosis include, multiple organ failure, diabetes, inborn errors of metabolism, growth hormone deficiency and alcohol abuse. In acute illness, the ketone bodies accumulate and cause metabolic acidosis which could be a life threatnening condition.

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Description

Product Name Format CAT.No Size
D-3 Hydroxybutyrate 3-HBDH/NAD LS BXC0542A R1: 1 x 50ml R2: 1 x 8ml R4: 1 x 5ml
D-3 Hydroxybutyrate Lyo BXC0541A R1: 1 x 50ml R2: 5 x 10ml R4: 1 x 5ml

 

Product Description

The Biorex Diagnostics D-3 Hydroxybutyrate (D3-HB) Assay is a ready-to-use reagent system for the quantitative determination of D-3-Hydroxybutyrate in human serum and plasma, providing essential insight into metabolic status and ketone body production. D3-HB is one of the primary ketone bodies produced during fatty acid metabolism, particularly under conditions where glucose availability is limited, such as fasting, prolonged exercise, or uncontrolled diabetes. Measurement of D3-HB is widely used in the detection and monitoring of ketosis, including diabetic ketoacidosis (DKA), a serious and potentially life-threatening complication of diabetes. Accurate assessment of D3-HB levels is therefore critical for clinical diagnosis, patient monitoring, and metabolic evaluation.

Key Features

  • Quantitative measurement of D-3-Hydroxybutyrate in serum and plasma
  • Clinically relevant for physiological and pathological ketosis, including diabetic ketoacidosis
  • Highly specific enzymatic method ensures accurate, sensitive, and reproducible results
  • Ready-to-use reagents simplify laboratory workflow and reduce preparation errors
  • Compatible with automated analysers, photometric assays, and routine clinical monitoring

Benefits
The Biorex D3-HB Assay delivers precise, reliable, and reproducible results, supporting diagnosis, monitoring, and research applications related to metabolic disorders and ketosis. Its enzymatic methodology provides high specificity for D3-HB, enabling accurate differentiation of metabolic states and early detection of abnormal ketone production. By providing consistent and dependable measurements, the assay supports timely clinical decision-making and effective management of patients at risk of ketoacidosis or other metabolic disturbances.

This assay is particularly valuable in hospital laboratories, emergency departments, diabetes clinics, and clinical chemistry settings where rapid assessment of ketone levels is required. Its ready-to-use format streamlines workflow, reduces pre-analytical variability, and ensures consistent performance across a range of laboratory environments. Compatibility with automated analysers allows seamless integration into routine testing platforms, supporting efficient, high-throughput analysis while maintaining accuracy and reliability.

In addition to clinical diagnostics, the Biorex D3-HB Assay supports research into energy metabolism, ketogenesis, and metabolic regulation, making it an important tool for advancing understanding of ketosis and improving patient outcomes.

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Additional information

Storage

2-8°C