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Ceruloplasmin

Ceruloplasmin is an acute phase protein. Incorporation of copper into Ceruloplasmin occurs during synthesis in the hepatocytes. After secretion from the liver, Ceruloplasmin migrates to copper requiring tissue, where copper is liberated and used. Decreased concentrations occur during recessive autosomal hepatolenticular degeneration (Wilson’s disease).

The Biorex Diagnostics immunoturbidimetric assay is intended for the in vitro quantitative determination of human Ceruloplasmin in human serum and plasma.

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Description

Product Name Format CAT.No Size
Ceruloplasmin Immunoturbidimetric without sample pre-dilution LS BXC0765A R1: 1 x 20ml R2: 1 x 4ml

 

Product Description

The Biorex Diagnostics Ceruloplasmin Assay is a ready-to-use reagent system for the quantitative determination of ceruloplasmin in human serum and plasma, providing essential insight into copper metabolism and liver function. Ceruloplasmin is a copper-binding glycoprotein produced in the liver, playing a key role in iron metabolism and antioxidant defence. Measurement of ceruloplasmin is widely used in the diagnosis and monitoring of disorders such as Wilson’s disease, Menkes disease, hepatic dysfunction, and inflammatory conditions. Altered ceruloplasmin levels may indicate impaired copper transport, liver disease, or acute phase responses, making it a valuable biomarker in clinical diagnostics.

Key Features

  • Quantitative measurement of ceruloplasmin in serum and plasma
  • Clinically relevant for evaluating Wilson’s disease, hepatic dysfunction, and copper-related metabolic disorders
  • Sensitive immunoturbidimetric method ensures accuracy and reproducibility
  • Ready-to-use reagents streamline workflow and minimise preparation errors
  • Compatible with automated analysers, manual spectrophotometry, and research applications

Benefits
The Biorex Assay delivers precise, reliable, and reproducible results, supporting diagnosis, monitoring, and research applications in metabolic and hepatic disorders. Its immunoturbidimetric methodology provides accurate quantification of ceruloplasmin levels, enabling clinicians to assess copper metabolism and identify abnormalities associated with liver disease or genetic disorders. By providing consistent and dependable measurements, the assay supports effective clinical decision-making and patient management.

This assay is particularly valuable in hospital laboratories, hepatology departments, clinical chemistry units, and research institutions focused on metabolic and liver diseases. Its ready-to-use format streamlines workflow, reduces pre-analytical variability, and ensures consistent performance across different laboratory environments. Compatibility with automated analysers allows seamless integration into routine testing platforms, supporting efficient, high-throughput analysis while maintaining accuracy and reliability.

In addition to clinical diagnostics, the Biorex Ceruloplasmin Assay supports research into copper metabolism, oxidative stress, and liver physiology, making it an essential tool for advancing understanding of metabolic disorders and improving patient outcomes.

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Additional information

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2-8°C