Description
| Product Name | Format | CAT.No | Size |
| a2-Macroglobulin | LS | BXC0889A | R1: 1 x 20ml R2: 1 x 4ml |
| a2-Macroglobulin | LS | BXC0889B | R1: 2 x 20ml R2: 1 x 8ml |
Product Description
The Biorex Diagnostics Alpha-2-Macroglobulin (A2M) Assay is a ready-to-use immunoturbidimetric reagent system designed for the quantitative determination of alpha-2-macroglobulin in human serum. Alpha-2-macroglobulin (A2M) is a high-molecular-weight plasma glycoprotein that plays a crucial role in inhibiting a wide range of proteases, thereby contributing to the regulation of proteolytic activity in the bloodstream. In addition, A2M is involved in immune system modulation, hormone transport, haemostasis, and complement system regulation, making it an important biomarker in clinical diagnostics.
Clinically, measurement of A2M is valuable in the assessment and monitoring of various conditions, including nephrotic syndrome, liver disease, diabetes, and other metabolic disorders. Altered levels of alpha-2-macroglobulin can provide insight into changes in protein synthesis, renal filtration, and inflammatory status. For example, elevated levels are often associated with nephrotic syndrome, while decreased levels may be observed in liver dysfunction, where protein synthesis is impaired. As such, A2M serves as a useful adjunct marker in evaluating overall patient health and disease progression.
The Biorex A2M Assay utilises a highly sensitive immunoturbidimetric method that ensures accurate, specific, and reproducible results across a wide analytical range. The assay is designed for seamless integration into both automated analyser systems and manual spectrophotometric techniques, providing flexibility for a variety of laboratory settings. Its ready-to-use format reduces preparation time, minimises handling steps, and helps to decrease the risk of procedural errors, supporting consistent and efficient laboratory workflows.
Key Features
• Quantitative measurement of alpha-2-macroglobulin in serum
• Clinically relevant for nephrotic syndrome, liver disease, diabetes, and metabolic disorders
• Immunoturbidimetric method ensures high sensitivity, specificity, and reproducibility
• Ready-to-use reagents for simplified workflow and reduced preparation errors
• Compatible with manual spectrophotometric techniques and automated analyser systems
Benefits
The Biorex A2M Assay delivers precise and dependable results that support the diagnosis, monitoring, and management of renal, hepatic, and metabolic conditions. Its robust analytical performance ensures consistent outcomes, while its ready-to-use design enhances laboratory efficiency and workflow simplicity.
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