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Anti-H

ABO blood groups consist of three main carbohydrate antigens; A, B and H antigens. The H antigen is found on all red cells with the exception of an extremely rare situation known as the ‘’Bombay Phenotype’’. The H antigen is made before either A or B antigens can be made, resulting in a reciprocal relationship between the amount of H and the amount of A and/or B on a red cell. Individuals with the A, B and AB alleles express glycosyltransferase activities that convert the H antigen to the A antigen or to the B antigen. Group A and B people therefore have less H than group O people.

The Biorex Diagnostics Anti-H blood grouping reagent is prepared from a Ulex Europaeus seed extract, diluted with a sodium chloride solution containing bovine albumin. This reagent is supplied ready for use and does not require any further dilution or addition.

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Description

Product Name CAT.No Size
Anti-H BGBH0002 1 x 2ml

 

 

Product Description

The Biorex Diagnostics Anti-H reagent is a ready-to-use lectin specifically formulated for the accurate detection of the H antigen on human red blood cells. The H antigen is a precursor for A and B antigen formation and is present in varying amounts across ABO blood groups. Its detection is crucial not only for confirming ABO blood types but also for identifying rare phenotypes such as the Bombay (Oh) blood group, where the H antigen is completely absent. Reliable identification of H antigen status ensures safe blood transfusions and accurate immunohaematology testing.

Key Features

  • Accurate H antigen detection – clearly identifies H-positive and H-negative red cells, supporting ABO blood grouping verification
  • Critical for rare phenotype identification – enables detection of Bombay (Oh) individuals who lack H antigen
  • Ready-to-use format – supplied as a stable liquid lectin extract, eliminating the need for preparation or dilution
  • Natural lectin source – derived from Ulex europaeus, providing consistent and specific reactivity
  • Clear and reliable agglutination – strong, reproducible reactions with H-positive red cells for easy interpretation

Benefits
Use of the Anti-H reagent allows laboratories to confirm ABO classifications with confidence, distinguish between high and low H antigen expression, and accurately identify rare H-negative phenotypes. Its ready-to-use format saves time and reduces the risk of handling errors, while the lectin’s natural specificity ensures reproducible results. Routine application supports safe donor–recipient matching, helps prevent transfusion reactions, and facilitates extended immunohaematology testing. This reagent is essential for hospital laboratories, blood banks, and reference immunohaematology facilities requiring precise ABO typing and rare phenotype identification.

By integrating the Biorex Anti-H reagent into standard laboratory workflows, healthcare providers can maintain high standards of transfusion safety, improve accuracy in blood group determination, and ensure reliable detection of clinically significant rare phenotypes, contributing to overall patient care and laboratory efficiency.

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Additional information

Storage

2-8°C