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Anti-FYa

The FYa and FYb antigens were reported in 1950 and 1951 respectively. Anti-FYa has been implemented in immediate and delayed Haemolytic Transfusion reactions and Haemolytic Disease in the new born. Indirect agglutination of red cells that carry the FYa – antigen occurs in the antiglobulin phase.  In the absence of the FYa– antigen, no indirect agglutination is generally observed.

The Biorex Diagnostics Anti-FYa reagent consists of human monoclonal antibodies diluted in phosphate buffer containing sodium chloride and bovine albumin. The reagent requires no further dilution or addition for recommended techniques.

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Description

Product Name CAT.No Size
Anti-FYa BGFYA002 1 x 2ml

 

 

Product Description

The Biorex Diagnostics Anti-FYa reagent is a ready-to-use monoclonal antibody solution specifically designed for the accurate detection of the FYa antigen in the Duffy blood group system on human red blood cells. The FYa antigen is clinically significant because antibodies directed against it can cause haemolytic transfusion reactions (HTRs) and, in certain cases, haemolytic disease of the newborn (HDN). Reliable identification of the FYa antigen is therefore critical to ensure transfusion safety, prevent alloimmunisation, and support extended phenotyping in hospital laboratories, blood banks, and specialist immunohaematology facilities.

Key Features

  • Accurate FYa antigen detection – clearly distinguishes FYa-positive and FYa-negative red cells, ensuring dependable donor and patient typing.
  • Indirect antiglobulin test (IAT) – provides sensitive and reproducible detection of clinically significant antibodies, including those present at low titres.
  • Clinically relevant – assists in preventing HTRs and HDN associated with anti-FYa antibodies, contributing to safer transfusion outcomes.
  • Ready-to-use format – supplied as a stable liquid reagent, eliminating the need for dilution or preparation and reducing laboratory handling errors.
  • Consistent monoclonal performance – high-quality formulation ensures reliable and repeatable results across multiple samples, even in complex antibody investigations.

Benefits
Routine use of the Anti-FYa reagent enables laboratories to accurately determine the FYa antigen status of donor and patient red cells, supporting extended immunohaematology panels and transfusion compatibility testing. Its ready-to-use format simplifies laboratory workflow, reduces errors, and saves valuable time while the monoclonal antibodies provide highly specific and sensitive detection, even for low-titre antibodies.

The reagent is particularly valuable for antibody screening and identification, ensuring safe transfusion in sensitised patients and facilitating selection of compatible donor units. Incorporating the Biorex Anti-FYa reagent into standard immunohaematology protocols enhances patient safety, supports extended blood group phenotyping, and helps prevent alloimmunisation-related complications. Its accuracy, reproducibility, and ease of use make it an essential tool for hospital laboratories, blood banks, and specialist transfusion services, providing confidence in laboratory results and ensuring effective patient care.

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Additional information

Storage

2-8°C