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Anti-D Blend

Antibody induced by D-antigen is the most frequent cause of haemolytic disease of the new-born. The Anti-D reagent is intended to be used to determine the presence or absence of the RhD antigen on the red blood cells. The test is based on the principle of hemagglutination. Red blood cells with the antigen will agglutinate in the presence of the reagent containing the corresponding antibody.

Biorex Anti-D IgG/IgM blood grouping reagent is a low protein blend reagent containing a human monoclonal IgM and IgG anti-D diluted in a phosphate buffer containing sodium chloride (0.9g%), bovine albumin (2.0g%) and macromolecular potentiators (1.5g%).

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Description

Product Name CAT.No Size
Anti-D Blend BGD00010 1 x 10ml
Anti-D Blend BGD01000 1000ml
Anti-D Blend BGD01010 10 x 10ml
Anti-D Blend BGD02210 221 x 10ml

 

 

Product Description

The Biorex Diagnostics Anti-D Blend reagent is a ready-to-use solution for the accurate detection of the RhD antigen on human red blood cells. Its high specificity and combined IgM/IgG formulation make it a critical tool for safe transfusions, antenatal screening, and immunohaematology investigations, helping prevent haemolytic transfusion reactions (HTRs) and haemolytic disease of the newborn (HDN).

Key Features

  • Reliable RhD antigen detection – identifies D-positive and D-negative red cells
  • IgG/IgM blend – IgM provides immediate-spin reactivity, while IgG allows indirect antiglobulin testing (IAT) for enhanced sensitivity
  • Clinically significant – essential for safe transfusion practices and HDN prevention
  • Ready-to-use reagent – stable liquid formulation, no preparation or dilution required
  • Enhanced sensitivity – includes macromolecular potentiators to improve antigen–antibody interactions

Benefits
Routine use of the Anti-D Blend reagent enables accurate RhD typing for both patients and donors, ensuring safe selection of compatible blood. Its combined IgM/IgG blend allows laboratories to detect weak D expression and low-titre D antigens, supporting comprehensive immunohaematology testing and preventing transfusion complications. The ready-to-use format reduces preparation errors, saves time, and streamlines laboratory workflows while maintaining reproducible performance across multiple samples.

The reagent is especially critical in antenatal care, where early and reliable RhD detection prevents alloimmunisation in D-negative mothers carrying a D-positive foetus, reducing the risk of HDN and improving neonatal outcomes. It also supports extended Rh phenotyping panels in hospital laboratories, blood banks, and reference immunohaematology facilities, complementing other Rh reagents such as Anti-C, Anti-c, and Anti-E for full Rh antigen profiling.

By incorporating Biorex Anti-D Blend into standard laboratory protocols, healthcare providers can maintain high standards in transfusion medicine, ensure patient and donor safety, and achieve reliable RhD typing in routine and advanced immunohaematology testing. Its combination of precision, sensitivity, and ease of use makes it an indispensable reagent for clinical laboratories and blood transfusion services.

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Additional information

Storage

2-8°C