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Anti-Cw

Since the description of the RhD antigen by Levine and Stetson in 1939, more than 40 other Rh antigen complexes have been identified. Apart from D the other major Rh antigens are C, E, c and e. The Cw antigen is one of the more rare antigens but Anti-Cw is a fairly common encountered antibody. Used separately, anti-Rh blood grouping reagents will indicate whether an individual expresses the corresponding antigen – an essential procedure in the determination of antibody specificity and selection of blood for transfusion of patients with Rh antibodies. Testing red cell samples with anti-C, anti-D, and anti-E, anti-c and anti-e will disclose the Rh phenotype from which the most probable genotype may be deduced.

The Biorex Diagnostics Anti-Cblood grouping reagent contains human monoclonal IgM antibody, diluted in a phosphate buffer containing sodium chloride, bovine albumin and a preservative. This reagent is supplied ready for use and does not require any further dilution or addition.

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Description

Product Name CAT.No Size
Anti-Cw BGCW0002 1 x 2ml

 

 

Product Description

The Biorex Diagnostics Anti-Cw reagent is a ready-to-use solution designed for the accurate detection of the Cw antigen, a rare but clinically significant component of the Rh blood group system. Reliable identification of this antigen is essential for safe transfusion practice, extended Rh phenotyping, and the prevention of haemolytic disease of the foetus and newborn (HDFN). Its precise formulation ensures consistent performance across clinical laboratories and blood banks, supporting both routine and specialized immunohaematology testing.

Key Features

  • Specific Cw antigen detection – accurately identifies Cw-positive and Cw-negative red blood cells
  • Direct agglutination method – produces clear, interpretable results for clinical use
  • Supports transfusion safety – prevents alloimmunisation by ensuring proper antigen–antibody matching
  • Ready-to-use format – stable liquid formulation requiring no preparation, minimizing laboratory errors
  • High-quality monoclonal IgM reagent – ensures consistent, reproducible results across multiple lots

Benefits
Use of the Anti-Cw reagent allows laboratories to reliably detect the presence or absence of the rare Cw antigen, facilitating accurate blood typing and antibody investigations. It supports transfusion compatibility testing by helping identify donors and patients at risk of developing anti-Cw antibodies, thereby preventing haemolytic transfusion reactions. The reagent is also valuable in antenatal screening and monitoring, contributing to the prevention and early detection of HDFN in pregnancies involving Cw incompatibility.

The ready-to-use formulation reduces preparation time, streamlines laboratory workflow, and minimizes handling errors, making it ideal for high-throughput clinical laboratories, hospital transfusion services, and specialist blood banks. Routine use enhances patient safety by ensuring reliable Rh phenotyping, supporting complex antibody panels, and providing confidence in both routine and extended immunohaematology testing.

By incorporating the Biorex Anti-Cw reagent into standard laboratory protocols, healthcare providers can maintain high standards in transfusion medicine, accurately identify clinically significant antigens and antibodies, and ensure safe, effective patient care. Its combination of specificity, reproducibility, and ease of use makes it an essential tool for modern immunohaematology laboratories.

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Additional information

Storage

2-8°C