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Anti-A1

The 2 major subgroups of blood group A are A1 and A2. Anti-A1 Lectin is used to differentiate these subgroups. Group A red blood cells which are agglutinated with Anti-ALectin are said to be of the subgroup A1. Those that do not agglutinate are majorly classified as A2. Agglutination of red cells that carry the A1 antigen occurs with the addition of the Anti-Areagent, following centrifugation. In the absence of the A1 antigen, no agglutination is generally observed.

Biorex Anti-A1 blood grouping reagent is prepared from a Dolichos biflorus seed extract, diluted with a sodium chloride solution containing bovine albumin. This reagent is supplied ready for use and does not require any further dilution or addition.

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Description

Product Name CAT.No Size
Anti-A1 BGA10002 1 x 2ml
Anti-A1 BGA10005 1 x 5ml
Anti-A1 BGA10010 1 x 10ml

 

 

Product Description

The Biorex Diagnostics Anti-A1 reagent is a ready-to-use solution designed for the accurate detection of A1 antigens and differentiation from A2 red blood cells within the ABO blood group system. Correct identification of A1 and A2 subgroups is critical for ensuring safe transfusion practices, accurate donor-recipient matching, and preventing ABO incompatibility reactions. Misclassification of ABO subgroups can lead to serious transfusion reactions or interfere with antibody identification, making a reliable Anti-A1 reagent an essential component of any immunohaematology laboratory. This reagent is suitable for hospital laboratories, blood banks, and reference facilities performing routine and extended blood typing.

Key Features

  • Precise subgroup differentiation – identifies A1-positive red cells while distinguishing A2 cells for accurate ABO subgrouping.
  • High-quality formulation – derived from Dolichos biflorus seed extract, stabilised in a sodium chloride solution with bovine albumin to ensure consistent performance.
  • Ready-to-use reagent – eliminates the need for dilution or preparation, reducing handling errors and saving valuable laboratory time.
  • Reproducible and reliable – manufactured under ISO 13485:2016 standards, ensuring consistent lot-to-lot performance across multiple batches.
  • Versatile application – compatible with both manual testing and automated blood typing systems, suitable for routine blood grouping, extended phenotyping, and antibody screening.

Benefits
Routine use of the Biorex Anti-A1 reagent enables laboratories to accurately distinguish between A1 and A2 red cells, preventing misclassification and improving transfusion safety. Its high sensitivity ensures reliable detection of weakly expressing A1 cells, supporting antibody investigation and accurate donor selection. The ready-to-use format simplifies workflow, reduces preparation time, and minimizes the risk of human error.

Incorporating Anti-A1 into laboratory protocols allows for precise ABO subgroup determination, aiding safe transfusions, supporting extended phenotyping panels, and maintaining high standards in immunohaematology practice. Its reproducible performance and ease of use make it an essential tool for hospital transfusion services, blood banks, and specialist reference laboratories, ensuring reliable results and enhanced patient care.

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Additional information

Storage

2-8°C