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Anti-CCP

Biorex Anti-cyclic citrullinated peptide antibody (Anti-CCP) is an in-vitro test for the quantitative determination of Anti-CCP in human serum or plasma. The diagnosis of rheumatoid arthritis (RA) often relies on clinical manifestations and laboratory tests as rheumatoid factor and C-reactive protein. However, the identification of citrulline as a target of a whole set of auto-antibodies detected in the sera of RA patients has led to the development of anti-CCP assays (antibody to cyclic citrullinated peptides) which possess a high specificity for RA. The clinical performance of anti-CCP assays has been further improved by the use of multiple citrullinated peptides, resulting in a second generation of anti-CCP assays.

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Description

Product Name Format CAT.No Size
Anti-CCP BXC0379A R1: 1 x 30ml R2: 1 x 10ml CAL: 6 x 0.5ml

Product Description

The Biorex Diagnostics Anti-Cyclic Citrullinated Peptide (Anti-CCP) Assay is a ready-to-use reagent system designed for the quantitative measurement of antibodies in human serum or plasma associated with rheumatoid arthritis (RA). Detection of these antibodies is highly specific for RA, making the assay a critical tool for early diagnosis, differentiation from other inflammatory arthropathies, and supporting timely clinical decision-making. Early identification of RA antibodies allows healthcare providers to initiate treatment sooner, potentially reducing joint damage and improving long-term patient outcomes.

Key Features

  • Quantitative Measurement: Provides precise and reliable antibody quantification, allowing laboratories to monitor levels accurately and track changes over time.
  • Clinically Relevant for Early RA Diagnosis: Detects RA in patients before clinical symptoms, such as joint erosion or swelling, become apparent, enabling proactive management.
  • Second-Generation Assay: Utilizes multiple citrullinated peptides to ensure high specificity and sensitivity, reducing the likelihood of false-positive or false-negative results.
  • Ready-to-Use Reagents: Pre-prepared reagents simplify laboratory workflow, minimise handling errors, and save time for technical staff.
  • Versatile Laboratory Compatibility: Fully compatible with automated analysers, manual ELISA methods, and research applications, offering flexibility across laboratory environments.
  • Reliable and Reproducible: Designed to provide consistent results across different operators and instruments, supporting both routine diagnostics and research studies.
  • Streamlined Workflow: Ready-to-use reagents and simplified procedures reduce preparation steps, increase throughput, and maintain reproducibility.
  • Research and Clinical Utility: Suitable for monitoring disease progression, evaluating patient response to therapy, and supporting studies on the mechanisms of RA and autoantibody profiles.

This assay delivers a dependable, sensitive, and user-friendly system for the detection and quantification of RA-associated antibodies. Its robust methodology and ready-to-use format ensure accurate results with minimal handling. By providing precise antibody measurement, this assay allows laboratories and clinicians to make informed decisions, monitor treatment efficacy, and maintain high-quality testing standards. Biorex’s assay is ideal for both diagnostic laboratories and research institutions focused on early RA detection and patient care.

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