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National Diabetes Month 2022  Diabetes is a chronic disease characterised by insulin resistance either due to the pancreas’s inability to produce enough insulin or due to the body’s inability to use the insulin it produces effectively. Insulin is the hormone that is responsible for the regulation of blood glucose 1. Approximately 537 million adults, aged 20-79 years of age, are living with diabetes and is projected to rise to 643 million by 2030 and 783 million by 2045. Moreover, 240 million (1 in 2) adults are living with diabetes but it is undiagnosed and 541 million adults are at an increased

The Role of Light Chains in Systemic Lupus Erythematosus (SLE)  This year Biorex Diagnostics are celebrating Lupus Awareness Month, placing a focus on the most common form of lupus, systemic lupus erythematosus (SLE). SLE is a complex and chronic autoimmune disease characterised by the appearance of autoantibodies against cytoplasmic and nuclear antigens and multi-organ inflammation 1. SLE affects 20-50 in every 100,000 individuals and is more commonly observed in women, with more than 90% of cases occurring in women, and begins at childbearing age 2, 3.   Pathogenesis of SLE The etiopathogenesis of SLE is controversial, limiting therapeutic interventions. What is understood is that

The Role of Lipoproteins in Atherosclerotic Cardiovascular Disease (ASCVD) Cardiovascular disease (CVD) is one of the leading causes of morbidity and mortality globally. Lipids and lipoproteins significantly contribute to atherosclerotic cardiovascular disease (ASCVD), a specific type of arteriosclerosis, whereby the arteries harden and plaque formations, or atheroma occur. The plaque build-up causes the arteries to narrow, restricting and eventually blocking blood flow. If the plaque bursts, this results in a blood clot. Whilst atherosclerosis is commonly perceived as a vascular issue, it can affect any artery in the body 1,2. Atherosclerosis is responsible for arteritis, myocardial infarction, cerebrovascular accident (CVA) and

Adverse Outcomes of SARS-CoV-2 Infection Caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus, coronavirus disease 2019 (COVID-19) is a major public health burden which can be devastating 1. As of 27th July 2022, there has been a total of 577,475,769 COVID-19 cases of which 6,407,989 have died. At this time, 27th July 2022, there are currently 23,803,240 infected patients of which 99.8% (23,761,474) of cases are in mild condition and 0.2% (41,766) of cases are serious or critical 2. The clinical severity of SARS-CoV-2 infection ranges from asymptotic to life-threatening illnesses 3. Today we will dive into some

The Mysterious Child Hepatitis Outbreak There has been an outbreak of severe acute hepatitis of unknown aetiology in children since 5th April 2022. 1,010 probable cases have been reported from 35 countries in five WHO Regions, as of 8th July 2022. Three additional countries have reported cases, however, as they are pending classification, they have not been included in the probable case count. On reviewing the probable cases, 2% (n=22) of children have died and 5% (n=46) of children have required liver transplants. There are possible links between severe acute hepatitis and a couple of respiratory illnesses, including the adenovirus with

To celebrate 20 years of trading, Biorex Diagnostics have unveiled a new visual identity to reflect the growth of the business over the years. The company is constantly seeking new ways to innovate and grow within our field. It was the business’ aim to be modern and in style with the healthcare industry but also to differentiate ourselves from other brands. “Biorex Diagnostics is a rapidly expanding innovative primary diagnostics manufacturer based in the United Kingdom. We specialise in the development, manufacturing and distribution of a range of Medical Diagnostics and Point of Care Tests for a global market.” Our new logo is

With the new Omicron variant sweeping the world faster than any other coronavirus strain before it, how concerned should we be? On 24th November 2021, the first Omicron case was announced in South Africa, (The Guardian), with the first sample of the virus dating back to 9th November 2021. Meaning this variant could already be across the world before it was founded and announced. On 26 November 2021, WHO designated the variant B.1.1.529 a variant of concern, named Omicron, on the advice of WHO's Technical Advisory Group on Virus Evolution (TAG-VE), (WHO). The omicron virus has an unusual profile in comparison to other COVID-19

On 1st November 2021, the COVID-19 death toll surpassed five million despite the ongoing vaccine rollout, (BBC News). Although the World Health Organisation have recently released that this number could be two to three times higher than official records, (WHO). These worrying statistics remind the public that following the social distancing guidelines from the government have previously outlined. Despite this recommendation no longer being essential in many parts of the world, it is still important to take it into consideration as the winter months continue and infection rates rise. Therefore, some ways to reduce the spread of COVID-19, save lives and protect

The COVID-19 pandemic, specifically the initial lockdown, saw the world come to a standstill, where people in the UK were told not to leave their homes for any reason bar the following; Shopping for basic necessities, as infrequently as possible One form of exercise a day Any medical needs, to provide care or to help a vulnerable person; and Travelling to and from work, but only where this is absolutely necessary and cannot be done from home. (GOV.uk) Despite one of the essential reasons for being able to leave the house included medical attention, many people were in such a state of

To raise awareness this World AIDs Day, it is important to focus attention on the research and development currently underway to combat HIV and AIDs. With the HIV virus, that causes AIDs, making its way to the western world in the early 1980’s, research into the virus has been constant since this time. It has recently been announced that ongoing research in Japan has shown that the HIV virus, ‘became undetectable in six out of seven test subjects’, (Neoscope). The Tsukuba Primate Research Centre have created a vaccine that was able to kill HIV in macaques during early trials. The macaques