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LISS Solution Diluent (For Blood Grouping)

Low-ionic strength solutions (LISS) increase the interaction of antigen and antibody in immuno hematologic reactions.

The solutions reduced of ionic strength are used to accelerate the interaction of antigen and antibody. That solution of saline containing less Na and Cl ions than normal isotonic salt solutions interfere less in the reaction between an antigen and antibody of complementary electrostatic charge. These solutions are known in immunohematology as Low Ionic Strength Saline (LISS). LISS solution is used for preparing 5% red cell suspensions for blood grouping as well as 0.8% red cell suspensions for cross matching, antibody screening, direct anti-human globulin test.

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Description

Product Name CAT.No Size
LISS Solution Diluent (For Blood Brouping) OBGLISS1 500ml

Product Description

The Biorex Diagnostics Low Ionic Strength Solution (LISS) is a ready-to-use reagent that enhances the rate and sensitivity of antigen–antibody reactions in immunohaematology testing. Its optimized formulation improves detection of clinically significant antibodies, reduces incubation time, and maintains red cell integrity.

Key Features
• Enhances antigen–antibody interactions – improves detection of weak or low-titre antibodies
• Reduces incubation time – accelerates serological reactions for efficient workflow
• Iso-osmotic formulation – maintains red cell stability during testing
• Ready-to-use format – eliminates dilution and minimizes preparation errors
• Versatile application – suitable for blood grouping, crossmatching, and antibody screening

Benefits
Use of LISS increases the sensitivity and reliability of serological testing, enabling accurate blood grouping, crossmatching, and antibody identification. Its ready-to-use, iso-osmotic formulation streamlines laboratory workflows, reduces handling errors, and supports consistent, reproducible results in both routine and advanced immunohaematology laboratories.

Additional information

Storage

2-8°C