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PAPP-A

Pregnancy associated plasma protein A (PAPP-A) is an important pregnancy protein which exists as a heterotetrameric complex with proMBP. Levels of PAPP-A are highest in pregnant women wherein values increase by a factor of 150 as compared to non-pregnant state.

The Biorex Diagnostics Pregnancy Associated Plasma Protein (PAPP-A), is intended for use in the quantitative determination of PAPP-A in human serum and plasma.

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Description

Product Name CAT.No Size
PAPP-A BXE0888A 96T

 

 

Product Description

The Biorex Diagnostics Pregnancy Associated Plasma Protein A (PAPP-A) ELISA kit is a highly sensitive and specific microplate enzyme-linked immunosorbent assay designed for the quantitative measurement of PAPP-A in maternal serum or plasma. PAPP-A is a critical placental biomarker whose concentration rises significantly during pregnancy. Accurate measurement of PAPP-A provides essential information for the early evaluation of placental function, fetal growth, and the risk of chromosomal abnormalities such as Trisomy 21. By enabling reliable detection, this assay supports prenatal screening and helps healthcare providers make informed clinical decisions during early pregnancy.

This ELISA kit employs a solid-phase, quantitative immunoassay methodology, ensuring high sensitivity and specificity for physiologically and clinically relevant PAPP-A concentrations. The assay is optimised for both serum and plasma samples, making it suitable for routine clinical workflows in prenatal care. Each kit includes ready-to-use reagents, standards, and controls, providing a streamlined and reproducible testing process across multiple runs and laboratory settings.

The Biorex Diagnostics PAPP-A ELISA kit supports early risk assessment in the first trimester, allowing clinicians to identify pregnancies at increased risk for chromosomal anomalies. Its high reproducibility ensures consistent results across different laboratories, enhancing confidence in prenatal screening programmes and maternal-fetal monitoring protocols. This assay is not only suitable for clinical diagnostics but also for research applications investigating placental function, maternal health, and fetal development.

Key Features

  • Quantitative Microplate ELISA – precise and reliable measurement.
  • High Sensitivity and Specificity – detects clinically meaningful concentrations.
  • Serum and Plasma Compatibility – suitable for routine prenatal screening workflows.
  • Supports First-Trimester Risk Assessment – used in screening for chromosomal anomalies.
  • Reproducible Results – consistent across diagnostic and research applications.
  • Comprehensive Kit Components – includes ready-to-use reagents, standards, and controls.

The Biorex Diagnostics PAPP-A ELISA kit provides a trusted, efficient, and clinically valuable solution for prenatal screening. By enabling accurate quantification of PAPP-A, the assay contributes to early risk detection, informed pregnancy management, and improved maternal-fetal health outcomes, supporting safer and more effective prenatal care.

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Storage

2-8°C