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Beta-2-Microglobulin Reagents

The Biorex Diagnostics β2-Microglobulin assay is intended for the in vitro quantitative determination of human β2-Microglobulin in human serum.

β2-Microglobulin is a low molecular weight protein (11800D) found of the surface of all cells except erythrocytes and the trophoblastic layer of the placenta. It is a constituent of the light chain of human histocompatibility antigens HLA, A, B and C. β2M is found on T and B cells and in tumour associated transplantation antigens. β2M may control the expression of antigens on the cell surface and their biosynthesis.

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Description

Product Name Format CAT.No Size
Beta-2-Microglobulin Immunoturbidmetric N/A BXC0090A R1: 2 x 12.5ml R2: 1 x 6ml CAL: 1 x 0.25ml

 

Product Description

The Biorex Diagnostics Beta-2-Microglobulin (β2M) Assay is a ready-to-use reagent system for the quantitative determination of β2-microglobulin in human serum, providing valuable insight into renal function, immune activity, and certain malignancies. β2-microglobulin is a low-molecular-weight protein present on the surface of all nucleated cells and is released into the bloodstream during normal cell turnover. It is freely filtered by the kidneys and almost completely reabsorbed in the proximal tubules, making its serum levels a sensitive indicator of glomerular filtration and tubular function. Elevated β2M levels may be associated with renal impairment, inflammatory conditions, and lymphoproliferative disorders such as multiple myeloma and lymphoma.

Key Features

  • Quantitative measurement of β2-Microglobulin in serum
  • Clinically relevant for kidney function evaluation, immune monitoring, and oncology assessment
  • Highly sensitive immunoturbidimetric method ensures accuracy and reproducibility
  • Ready-to-use reagents simplify workflow and reduce preparation errors
  • Compatible with automated analysers, manual spectrophotometric methods, and research applications

Benefits
The Biorex β2-Microglobulin Assay delivers precise, reliable, and reproducible results, supporting diagnosis, monitoring, and research applications in nephrology, immunology, and oncology. Its immunoturbidimetric methodology enables accurate quantification of β2M across clinically relevant ranges, assisting clinicians in evaluating renal function and identifying conditions associated with increased cell turnover or immune activation. By providing consistent and dependable measurements, the assay supports effective clinical decision-making and patient management.

This assay is particularly valuable in hospital laboratories, nephrology units, oncology departments, and clinical chemistry settings where assessment of renal and immune-related conditions is required. Its ready-to-use format streamlines workflow, reduces pre-analytical variability, and ensures consistent performance across laboratory environments. Compatibility with automated analysers allows seamless integration into routine testing platforms, supporting efficient, high-throughput analysis while maintaining accuracy and reliability.

In addition to clinical diagnostics, the Biorex β2-Microglobulin Assay supports research into renal physiology, immune system activity, and tumour biology, making it an essential tool for advancing understanding of disease processes and improving patient outcomes.

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Additional information

Storage

2-8°C