Anti-CDE

Since the description of the RhD antigen by Levine and Stetson in 1939, more than 40 other Rh antigen complexes have been identified. With the exception of the C, c, E and e and perhaps C^w, few of these antigens or their corresponding antibodies are controlled by a series of closely linked loci on chromosome 1, the genetic contribution from each parent being inherited as a haplotype e.g. Cde, cDE etc. Used separately, anti-Rh blood grouping reagents will indicate whether an individual expresses the corresponding antigen – an essential procedure in the determination of antibody specificity and selection of blood for transfusion of patients with Rh antibodies.

The Biorex Diagnostics Anti-C reagent is for the in vitro detection and identification of the human C blood group antigen by direct agglutination.